Endocrine Abstracts

Objectives: Ultrasound-guided fine needle aspiration biopsy (US-FNAC) technique has the advantage of obtaining tissue for cytological examination. The diagnostic yield may depend on factors related to both technical aspects and the lesions sampled. However, the variability between experienced and inexperienced physicians in obtaining adequate cytological sample has not been specifically studied previously. The aim of the study was to determine whether there is a difference in ...

Objective: The evidence regarding association between thyroid diseases and benign and malign breast diseases is increasing. It has been shown that thyroid disorders are more frequent in those with benign breast diseases and that different thyroid diseases have associations with benign and malign breast diseases and their outcomes. In this study, we aimed to reveal the frequency of benign breast conditions in patients with nodular thyroid disease and Hashimoto’s disease.</...

Objective: Ultrasonographic (US) echogenic micro-foci are frequently seen in papillary thyroid carcinoma (PTC). General belief is that microcalcifications represent psammoma bodies. But the subject is debatable and other sonographic intranodular echogenic figures can be seen in PTC. We aimed to examine the nonshadowing echogenic figures and their histopathological correlations in PTC.Methods: We prospectively collected US video records of PTC cases with ...

Introduction: Previous reports have shown that subjects with insulin resistance have increased thyroid volume and nodule prevalence. We investigated the effects of metformin on thyroid volume and nodule size.Methods: This prospective data were gathered on newly diagnosed subjects with insulin resistance (n=100, 68 female, 32 male) between August 2008 and May 2010. Measurements of thyroid hormones and thyroid ultrasonography was performed in all ...

Objective: The metabolic syndrome (MetS) is a cluster of metabolic abnormalities with insulin resistance (IR) as a major characteristic. It has been recently questioned that MetS and its related components are associated with functional and morphological alterations of thyroid gland. Aim of our study is to examine thyroid volume and nodule prevalence in patients with MetS in a mild-to-moderate iodine deficient area.Design: Two hundred and seventy-eight p...

Objective: Efficacy of eutectic mixture of local anesthetics (EMLA) cream and the needle-free injection of local anesthesia for reducing the pain associated with fine-needle aspiration biopsy (FNAB) of thyroid nodules was previously reported. However, direct comparison of the analgesic efficacy for both methods has not been established yet. The aim of this study was to compare the analgesic efficacy of EMLA cream and needle-free injection of lidocaine for FNAB-associated pain....

Objective: Thyroid hemiagenesis is a rare form of thyroid dysgenesis, in which one thyroid lobe fails to develop. The true prevalence of this rare abnormality is about 0.05–0.2% in normal population. We aimed to determine prevalence of thyroid hemiagenesis in patients with various thyroid disorders and a normal population in a mild to moderate iodine-deficient area.Subjects and methods: The clinical and thyroid ultrasonography records of 4.833 patie...

Objective: Morphologic and functional platelet abnormalities have been previously reported in patients with type 2 diabetes mellitus (DM) and some of these abnormalities have been linked to increased cardiovascular risk. Mean platelet volume (MPV) informs not only about platelet size, but also about its functions. Larger platelets bear more thrombotic potential. Higher MPV values have been correlated with cardiovascular events in the short and long run. Previous studies have d...

Distant metastases as initial manifestation of follicular thyroid carcinoma is rare. We report a case of an unusual initial presentation of follicular thyroid carcinoma on follow-up. A 52-year-old woman presented with a 12-month history of progressively enlarging mass in the anterior chest wall. The mass was fixed to the chest wall, measuring 12×10 cm in diameter. Computed tomography demonstrated a lobulated soft-tissue mass (17×11×6 cm) destructing sternum and ...

To asses the presence of antibodies to BIP/GRP78, which is a chaperon of endoplasmic reticulum and has immune modulating and antiapoptotic effects in Hashimoto’s thyroiditis.The study included 62 patients with autoimmune thyroiditis. Of these, 20 had euthyroid, 27 had subclinical hypothyroid, and 15 had hypothyroid Hashimato’s thyroiditis. A control group including 37 healthy patients also participated in the study.There ...